Acute Interval and Continuous Moderate Intensity Exercise Enhanced Circadian Thermogenic Activity through Browning related Genes in Obese Adolescent Female

Thermogenesis is associated with oxidation activity in muscle and fat tissue, the target of non-pharmacological therapy preventing increase obesity. This research was designed to reveal circadian profile thermogenic gene expression after acute interval continuous moderate-intensity exercise. The subjects were 22 randomly selected obese adolescent females who met predetermined inclusion criteria. study then divided into three groups: control group (CG), exercise (AIMIE), (ACMIE). Acute performed by running on a treadmill for 40-45 minutes, while defined as 60%-70% maximum heart rate (HRmax). blood samples collected initially (pre-exercise), followed 10 6 hours, 24 hours post-acute treatment. Measurement peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1α) fibronectin type III domain 5 (FNDC-5) expressions protein level confirmed enzyme-linked immunosorbent assay (ELISA) method. Data analyzed using one way-ANOVA two significant 5%. findings suggest substantial PGC-1α FNDC-5 compared before workout. A difference between AIMIE ACMIE (p ≤ 0.05) has been observed. However, there no ≥ 0.05). In conclusion, thermogenesis-related genes. Hence, might be potential prevent, reduce, increasing prevalence